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Cell Nomenclature SHEF-3
hESCreg Database SHEF-3 entry
UKSCB Acc. No. R-05-008
Provenance Caucasian, male
1. Bae, D., Mondragon-Teran, P., et al., 2012, Hypoxia enhances the generation of retinal progenitor cells from human induced pluripotent and embryonic stem cells. Stem Cells Dev., 21(8):1344-55. Epub 2011 Oct 27.
2. Kalisz, M., Winzi, M., et al., 2012, EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression. Developmental Biology, 362(1): 94-103.
3. Barbaric, I., Jones, M., et al., 2011, High-content screening for chemical modulators of embryonal carcinoma cell differentiation and survival. J. Biomol. Screen., 16(6):603-17. Epub 2011 May 18.
4. Bone, H.K., Nelson, A.S., et al., 2011, A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. Journal of Cell Science, 124(12): 1992-2000.
5. Fazeli, A., Liew, C.G., et al., 2011, Altered patterns of differentiation in karyotypically abnormal human embryonic stem cells. Int. J. Dev. Biol., 55(2):175-80.
6. Hernandez, D., Ruban, L. and Mason, C., 2011, Feeder-free culture of human embryonic stem cells for scalable expansion in a reproducible manner. Stem Cells Dev., 20(6):1089-98. Epub 2011 Jan 23.
7. Lim, H.J., Han, J., et al., 2011, Biochemical and morphological effects of hypoxic environment on human embryonic stem cells in long-term culture and differentiating embryoid bodies. Mol. Cells, 31(2):123-32. Epub 2011 Jan 18.
8. Wright, A., Andrews, N., et al., 2011, Mapping the stem cell state: eight novel human embryonic stem and embryonal carcinoma cell antibodies. Int. J. Androl., 34(4 Pt 2):e175-87; discussion e187-8. Epub 2011 Jun 9.
9. International Stem Cell Initiative, 2011, Screening a large, ethnically diverse population of human embryonic stem cells identifies a chromosome 20 minimal amplicon that confers a growth advantage. Nat. Biotech., 29(12): 1132-1144.
10. Aflatoonian, B., Ruban, L., et al., 2010, Generation of Sheffield (Shef) human embryonic stem cell lines using a microdrop culture system. In Vitro Cell. Dev. Biol. Anim., 46(3-4):236-41. Epub 2010 Mar 12.
11. Cogan, N., Baird, D.M., et al., 2010, DNA damaging bystander signalling from stem cells, cancer cells and fibroblasts after Cr(VI) exposure and its dependence on telomerase. Mutat. Res., 683(1-2):1-8.
12. Ramos-Mejia, V., Melen, G.J., et al., 2010, Nodal/Activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage. Mol. Ther., 18(12):2173-81. Epub 2010 Aug 24.
13. Aflatoonian, B., Aflatoonian, R., et al., 2009, Embryoid bodies from human embryonic stem cells form a niche for male germ cell development in vitro. Papers contributed to the 9th International Congress of Andrology, P169-174.
14. Aflatoonian, B., Ruban, L., et al., 2009, In vitro post-meiotic germ cell development from human embryonic stem cells. Human Reproduction, 24(12): 3150-3159.
15. Kubikova, I., Konecna, H., et al., 2009, Proteomic profiling of human embryonic stem cell-derived microvesicles reveals a risk of transfer of proteins of bovine and mouse origin. Cytotherapy, 11(3):330-40, 1 p following 340.
16. Catalina, P., Montes, R., et al., 2008, Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties? Mol. Cancer, 7:76.
17. Liew, C.G., Draper, J.S., et al., 2007, Transient and stable transgene expression in human embryonic stem cells. Stem Cells, 25(6):1521-8. Epub 2007 Mar 22.
18. Dean, S.K., Yulyana, Y., et al., 2006, Differentiation of Encapsulated Embryonic Stem Cells After Transplantation. Transplantation, 82(9): 1175-1184.
19. Inniss, K. and Moore, H., 2006, Mediation of apoptosis and proliferation of human embryonic stem cells by sphingosine-1-phosphate. Stem Cells Dev., 15(6):789-96.
20. Draper, J.S., Moore, H.D., et al., 2004, Culture and characterization of human embryonic stem cells. Stem Cells Dev., 13(4):325-36.
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Authors of this ToxBank wiki page

David Bower, Glenn Myatt
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