Beta-Naphthoflavone
From ToxBankWiki
Executive Summary Information
Compound | Β-Naphthoflavone |
Toxicities | Modulation of lipid metabolism with increased cholesterol metabolism and steatosis. |
Mechanisms | Β-Naphthoflavone is a mechanism of action standard for activation of the AHR transcription factor. |
Comments | The classic toxicities of thymic atrophy, wasting syndrome, and tumor promotion associated with activation of AHR by dioxins are highly species specific and in part a reflection of the extremely long in vivo half-life of the dioxins. |
Feedback Contact | Gold Compound Working Group (GCWG) |
Beta-Naphthoflavone | |
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Identifiers | |
Leadscope Id | LS-2162 |
CAS | 6051-87-2 |
DrugBank | DB06732 |
ChemSpider | 2271 |
Pathway DBs | |
Assay DBs | |
PubChem CID | 2361 |
ChEMBL | 26260 |
Omics DBs | |
Properties | |
ToxCast Accepted | no |
Toxic Effect | Steatosis |
ToxBank Accepted | yes |
Approved on | 20131001 |
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PubMed references
The following resource link will perform a PubMed query for the terms " Beta-Naphthoflavone " and "liver toxicity".
Beta-Naphthoflavone Search
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Calculated/Predicted Properties
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