Human Recombinant Oncostatin M (PHC5015)
From ToxBankWiki
Human Recombinant Oncostatin M (PHC5015)
Human Recombinant Oncostatin M (PHC5015)
Molecular Description
Molecular Weight | 26 kDa |
Glycosylation |
Biological Source
Name | E. coli |
Recombinant or animal source | Recombinant |
Characterisation Data
PAGE with antibodies | |
Cell culture testing e.g. growth promotion, cytokine expression |
Quality Control Parameters
Biological assay/activity | ED50 ≤2 ng/mL (≥5 × 105 units/mg). The biological activity is determined by measuring the oncostatin Mconcentration dependent stimulation of proliferation of TF–1 cells. The suggested concentration range for in vitroactivity studies is 0.2–20.0 ng/mL. The optimal concentration should be determined for each specific application.Oncostatin M is observed to exert variable, cell type dependent effects. For example, oncostatin M is observed tostimulate the growth of normal fibroblasts and AIDS–related Kaposi sarcoma cells, but is observed to inhibit thegrowth of A375 melanoma cells. |
Company | Product Link |
---|---|
Life Technologies | PHC5015 |
Publications | |
SEURAT Protocols | Search for Protocols in the ToxBank Data Warehouse |
SEURAT Data | Search for Data in the ToxBank Data Warehouse |
Other Links |