E-4031
From ToxBankWiki
Executive Summary Information
Compound | E-4031 |
Toxicities | Cardiac arrhythmias |
Mechanisms | E-4031 is a selective Kv11.1 potassium ion channel (aka human Ether-à-go-go-Related Gene, hERG) antagonist. |
Comments | E-4031 is a preferred reagent for characterizing inhibition of the hERG ion channel in cardiomyocytes. |
Feedback Contact | Gold Compound Working Group (GCWG) |
E-4031 | |
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Identifiers | |
Leadscope Id | LS-183700 |
CAS | 113558-89-7 |
Pathway DBs | |
Assay DBs | |
PubChem CID | 3185 |
Omics DBs | |
Properties | |
ToxCast Accepted | no |
Toxic Effect | Cardiac arrhythmias |
ToxBank Accepted | yes |
Target | Class III antiarrhythmic potassium channel blocker |
Toxicities | Cardiac arrhythmias |
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PubMed references
The following resource link will perform a PubMed query for the terms " E-4031 " and "liver toxicity".
E-4031 Search
The following resource link will perform a PubMed query for the terms " E-4031 " and "cardio toxicity".
E-4031 Search
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